Rolex

We are happy to announce that we will be attending the Rolex Kentucky on April 26-29, 2012. We are very excited and cannot wait to meet so many new people there. It is our goal to come to the needs of our customers. We are dedicating our time to travel to where your need is. We are hoping through being present at the Rolex that we will get some more Cur-Ost EQ lovers that will have the ability to experience what this wonderful product can do, for themselves. The Rolex is a wonderful way to network and get to know many of the individuals, that we as a company, look up to. We are very excited for all the new and upcoming events going on within our company…we will definitely keep you posted!!!! http://www.rk3de.org

New product release

Tags

, , , , , , ,

We are proud to announce the release of our newest version of Cur-OST for horses called Cur-OST GREEN. This formula combines the powerful antiinflammatory capabilities of Curcumin with Boswellia in a bioavailable “green” base of alfalfa and spirulina. The product not only helps to control chronic inflammation, but also supplies needed antioxidants, vitamins and minerals naturally through the alfalfa and spirulina components. We have used the new blend in our equine facility on patients for several months and have noted marked improvements in many situations. We have also noted an improvement in skin, hair and hoof growth. The new blend also contains Ashwaghanda extract that has antiinflammatory as well as anti-stress capabilities, helping the body to adapt and recover. In many cases, we have had reports of a calming effect in more high strung horses in addition to resolving health problems. Come see us at www.cur-ost.com for more information regarding our product lines. Thank you to all of our loyal customers for their support of our products.

Thank you again,

Tom Schell, D.V.M.

Calcified Knees

Betty,

Thank you for your question.  Your mare sounds like she is in a tremendous amount of pain in her knees due to calcification associated with arthritis.  Arthritis is a very debiliating condition and one that is best controlled in an early stage.  I agree with your veterinarian that surgery is probably not an option, as in most cases, removal of bones spurs in the joints alleviates pain in the short term, but the process of degeneration continues and the joints are soon in poor shape again.  I cannot offer you anything in terms of reducing the bone spurs or areas of calcification that are present within the joint, but we may be able to control the pain and inflammation associated with the condition.  The bone spurs are creating soft tissue inflammation around and within the joint, which is then associated with swelling, reduced movement and of course pain.  The inflammatory mediators involved in this process have been shown to be inhibited or at least reduced in our clinical trials using Cur-OST.  The primary ingredient in Cur-OST, being Curcumin, has also been shown in numerous human clinical trials to help not only reduce the pain and inflammation, but also slow the course of the disease.  This condition is very common in the older horse and in our clinical practice, we have had several geriatric horses with arthritis respond very favorably.  The bone spurs are still present in these cases, but the inflammation associated with the condition is more controlled, leading to a higher quality of life for the horse.  I would encourage you to give Cur-OST a try as it might provide the relief you are seeking for your mare.  I hope this answers your question.

Thank you,

Tom Schell, D.V.M., DABVP

Laminitis Questions

Dr. Schell,

I have a gelding that was diagnosed with laminitis 2 years ago and we have struggled with his condition ever since.  He has had special shoes applied, turned out onto a dry lot and fed low starch feeds.  He is also on bute daily for pain as well as several other medications to control his condition.  Is there anything that your product, Cur-OST, can offer him that he hasn’t had already?

Signed,

Painful in Alabama

This is a very typical type of question that I receive via email.  Many horse owners are struggling with laminitis, especially this time of the year.  Springtime brings with it new grass growth that can be very high in carbohydrate or sugar levels.  This sugar not only leads to weight gain, but can contribute to the development of insulin resistance as well as a host of other health conditions in the horse.  The typical therapies for a foundered or acutely laminitic horse are to remove them from pasture, dry lot confinement, low starch feed, foot support by means of special shoes, pain medication and possibly a few supplements.  I have to admit that I too, as a veterinarian, followed this train of thought for over a decade and yes, we did see some horses improve clinically, but what a terrible life they lived, confined to a dry lot while all their buddies are out on pasture.  They are almost being punished for enjoying their life and eating.  The long story short is that our clinical research at Nouvelle Veterinary is indicating that many of these horses, laminitic and insulin resistant, are presenting with moderate oxidative stress (see previous blogs).  The source of the oxidative stress is most likely underlying metabolic problems and chronic inflammation.  It becomes a vicious cycle, as the oxidative stress builds, more cellular damage is done and more inflammation is produced, making the condition of laminitis and insulin resistance worse.  I think the key is to determine if oxidative stress is present in these cases and then treat accordingly.  Cur-OST was designed to help reduce inflammation naturally as well as combat and neutralize free radicals in oxidative stress conditions.  In our hospital setting, this is exactly how the product works.  In a high percentage of laminitic horses admitted to our hospital, we can place them on the Cur-OST product twice daily along with foot support and very low doses of phenylbutazone, and have them show marked improvement in their lameness within 3-5 days.  This is a far cry different than what we would expect with traditional therapies.  Cur-OST is a different approach to equine inflammatory conditions, but one that shows tremendous promise.

So…to answer the question, YES, I think Cur-OST has ALOT to offer any horse with laminitis.

Tom Schell, D.V.M.

www.cur-ost.com

Alternative Therapies

Alternative therapies…what exactly does that mean?  To many, it means voodoo type of medicine involving witches’ brew and an eye of newt, as a friend of mine commonly notes.  The truth of the matter is that alternative therapy encompasses a large group of options including nutrients, herbs, acupuncture, massage therapy, meditation and the list goes on.  Many of these therapies have been utilized for centuries with well documented results.  So, why is it that so many people frown upon alternative therapies or quickly brush them off, even when traditional Western medicine has failed them?  Why do so many physicians quickly dismiss the simplest of vitamin/mineral supplements as an added support measure for their clients?

If you watch the news enough, it seems that pharmaceutical medications have cornered the market on commercials.  It seems there is a medication for almost every malady afflicting man kind.  Every negative symptom that you can imagine probably has a prescription that can counteract it.  Is this necessarily good?  Probably not.  Lately, it seems that many of these prescription medications have had some negative publicity.  There are constant reports of potential negative side effects being reported as well as negative interactions with other prescription medications.  Some well know statin medications were recently highlighted as being inferior in one study when compared to a commonly utilized b-vitamin, Niacin, in reduction of LDL and elevation of HDL cholesterol.  Did you also know that the statin medications are also commonly linked to a reduction in the necessary Co-enzyme Q10 that is needed for vital cellular energy production?  This association could explain why some statin users may be more predisposed to cardiac events.

The overall point is that we, as a general population, are bombarded with commercials and advertisements pushing prescription medications.  We feel a few pills in a bottle are the answer to our everyday problems, when in fact, we probably should be paying more attention to our overall health and lifestyle.  A few prescription pills will not negate years of bodily neglect, however we are led to believe the opposite.

If one stays current on human medical research, it soon becomes obvious that many diseases can be prevented or slowed in progression through good nutrition.  A poor diet as well as negative lifestyle lead to health problems that may or may not be able to be reversed.  Vitamins and minerals are being linked heavily with various forms of cardiovascular disease as well as cancer.  Deficiencies of these specific vitamins/minerals are noted in afflicted patients.  So, this tells us that maybe, just maybe, we could prevent the onset or at least slow the onset of disease through supplementation.  For instance, in cardiovascular disease, there is a marker utilized called C-reactive protein.  This is an acute phase protein that can be used to determine our overall risk of cardiovascular disease.  It is easily screened for, but unfortunately many physicians do not investigate.  The point is that levels of C-reactive protein as well as homocysteine can be lowered through the use of vitamin B6 and B12 .  This has also been well documented, but unfortunately not well publicized.  Another area of hot debate is levels of vitamin D3 and ascorbic acid (vitamin C).  There is much research out there to support increasing patient levels of both vitamins might actually support immune function and control or negate several diseases.

So, here I sit, as both a veterinarian and avid researcher, wondering why the general population is not taking better care of themselves through nutrition.  In my eyes, the answer is twofold: convenience and ignorance.  People eat they way they do for pure covenience, thus the reason fast food chains florish.  Another reason they eat they way they do is relative ignorance of nutrition and the overall impact on health.  No offense meant to our readers.  I encourage my clients, friends and relatives to explore and research their disease conditions and become knowledgable of recent advances or insights.  This is how we can become more educated and thus pose more meaningful questions to our caregivers, questioning our treatments and medications.

Chinese medicine is a fascinating area to me and one that I am just really beginning to know and understand.  Chinese medicine is based on the idea of holism, in which the body is viewed as a whole or entirety.  In order to be healthy, our bodies must be in balance.  This balance is thrown off kilter by anything ranging from emotions to diet as well as toxin exposure.  The overall point being that when the body is afflicted with disease, we are out of balance as a unit and must regain balance in order to obtain health.  Chinese medicine utilizes many forms of therapy including herbs, acupuncture and massage to achieve and regain balance.  If you are not familiar with Traditional Chinese medicine, I’ d encourage you to explore it further.  Personally, I am an avid user and recipient of acupuncture and herbal therapies and have noted a marked improvement in my overall health.

So, the original question was why aren’t these therapies utilized more often?  Well, they are utilized, but by specialized practitioners and only the avid health conscious individual seems to seek them out.  Alternative therapies are also unfortunately utilized as a last resort or at the end stages of disease, in which many cases fail purely due to disease progression and then alternative medicine gets a bad report card.  I believe that alternative therapies should be utilized in the beginning stages of any disease, whether it is the common cold or early diagnosed cancer.  The majority of these therapies can be utilized with traditional western medicine with no negative interactions.  Many cases actually benefit from the utilization of both eastern and western medicine. 

Our bodies are complex machines, requiring many nutrients to function on a daily basis.  When our bodies are sick or diseased, the nutrient levels become depleted and thus the demand is higher.  So, why is it not common knowledge to supplement an ailing body?  Individual researchers such as Linus Pauling stated the body’s need for vitamins such as ascorbic acid increased with the severity of disease.  Linus Pauling was able to document in several hundreds of cases that the administration of intravenous vitamin C could abolish symptoms related to maladies ranging from common colds to cancer and even went on to recommending every individual should supplement with very high doses of Vitamin C on a daily basis.  He is not alone in this thought process and there are numerous alternative clinics in the US that utilize these types of therapies for their patients.

I guess my point is to become educated about your disease, question every treatment and every prescription.  Too many individuals are consuming so many prescriptions that they have no idea why.  This is not only an expensive habit, but a concerning one.

Tom Schell, D.V.M.

www.cur-ost.com

Instant Gratification

Hello again.  Instant gratification…. a term that is being tossed around in society with high frequency lately.  For the past 2 years, we have been researching our Cur-OST product in horses for various inflammatory conditions with dramatic results in some cases.  Yes, we have had some horses fail to respond to the product, but honestly, I don’t perceive it as product failure but more so failure on the owner’s end to appreciate the results gained.  Our products have been available to the general public for about one year now and heavily used in our equine practice.  It is interesting to get feedback from individuals that are using the product for the first time.  Some are very happy with the results while others appear rather negative, noting no improvement.  This gets me down, not only because we have researched and developed the product but because I have seen the difference in over 100 of our own patients.  I have had owners contact us stating that their horse was on daily bute for arthritis, but they discontinued it and placed him/her on the Cur-OST, but after 2 weeks time, they do not see a difference in the lameness.  When asked if the horse is still off bute, they comment, YES.  When asked if the lameness is worse, they say NO,  but they somehow are not making the connection that the product is taking the place of bute on a daily basis, helping to reduce inflammation and keeping the lameness under control without the use of prescription medication.  This is the healthy way to go, more natural and with a reduced risk of ulcers and associated problems with daily bute usage.  Nothing will make a lameness go away completely and in most cases, the lameness is mechanical due to bone spur formation so our goal is to alleviate associated pain and inflammation, but more than likely the lameness will remain to a certain extent.   The same thing holds true to any chronic inflammatory condition, whether that be laminitis, arthritis or navicular syndrome.  In chronic situations, bone structures shift, scar tissue forms and animals form lameness habits.  These situations usually cannot be reversed but may be improved over time, certainly not overnight.  Our research focused on more acute conditions, especially laminitis.  Those were the horses that seemed to respond most favorably and in the shortest period of time.  All inflammatory conditions have a good chance of responding to Cur-OST, but it will take time. 

First, understand what your goal is with therapy for your horse, irregardless of what product you are chosing to use.  If your goal is to get the horse through the next event and that is it, then there are more rapidly acting options out there.  If your goal is to reduce the horse’s dependence on prescription medications and joint injections, then supplements like Cur-OST may offer some help, but change takes time, especially in chronic situations.  If it takes years to develop a problem, it will at least take a few months to improve.

Thank you for following us and as usual, if there are questions or comments, feel free to drop us an email.

Tom Schell, D.V.M, DABVP

www.cur-ost.com

Increased Awareness

Things are definitely beginning to look up lately.  Many encouraging signs that our research and product information is spreading.  This was our hopes and desires in the beginning, help the horses with natural agents that are proven effective.  Change is a lengthy process though and takes time.  We have many good veterinary friends as well as horse owners that are helping to spread the news.  A big thanks to them.  We have also been contacted by several laymen equine journals for possible article publishing.  That would be a welcomed medium to help educate horse owners as well as veterinarians as to the whole impact of inflammation on the body.  We have also just finalized and submitted an article on the impact of oxidative stress on insulin resistance in horses to well know equine veterinary journal for publishing.  The process to get to that point is slow, but we are hopeful.  Once again, anything that helps to spread the news is welcome.

Please visit our website as our partners have been working hard on updating with more current educational material, and as usual, if there are any questions or thoughts, please email them to us.

Thanks,

Tom Schell, D.V.M., DABVP

www.cur-ost.com

Contacts

I apologize and keep forgetting to leave our contact information for those wishing for more information. Please visit our website at www.nouvelleveterinary.com for more information about our research as well as products. Feel free to contact us via email with any questions or comments.

Thank you,

Tom Schell, D.V.M, DABVP

Oxidative Stress

Tags

, , , , , ,

Oxidative stress….the word for today it seems.  For the two years, we have been exploring the use of our product, Cur-OST, in horses with arthritis, navicular disease and laminitis.  We have seen some dramatic results, but were somewhat perplexed as to why.  We published one trial in the AHVMA journal this year revealing how we were able to reduce joint inflammatory mediators with use of the product.  By reducing these mediators, we were able to relieve pain and inflammation, which lead to our results clinically.  About 4 months ago, we purchased a device called the FRAS-4.  This stands for Free Radical Analytical System, made in Italy and just recently released in the USA.  The device was designed and intended for human oxidative stress research, but we have implemented in our clinical trials as well as in our veterinary practice.  So, what does the device measure.  Specifically, it measures the levels of free radicals or reactive oxygen species as well as the antioxidant potential in a small sample of blood from the patient.  What we are looking for is evidence of OXIDATIVE STRESS.  Oxidative stress is a clinical situation in which free radicals outnumber the ability of the antioxidants.  Free radicals or ROS are unstable oxygen derivatives that can lead to clinical disease such as inflammation if the levels get too high.  Antioxidants are molecules that essentially neutralize the free radicals, keeping them in check if you will.  There is a tremendous amount of human research that is pointing towards oxidative stress as being a major component to various diseases, including diabetes, cancer, bowell disorders, cardiovascular disease and many others.

So…what have we found out.  In our horses trials, specifically those with insulin resistance and laminitis, we have discovered that about 98% of those patients are undergoing oxidative stress.  When we put them on the Cur-OST product and recheck them in 14 days, we note that their oxidative stress levels are markedly improved as well as the overall lameness of the horse.  We are currently in the process of trying to get our data published for equine veterinarians to view.

After reviewing this new trial data as well as our past data, it appears that the Cur-OST blend is working via two methods to improve patient health and lameness: reducing inflammatory proteins such as PGE-2 and MMP-9 as well as reducing free radical levels and increasing antioxidant potential.  That is incredible and so far no side effects…only benefits.

We have been also reviewing overall health of dogs with the FRAS-4 device and are finding similiar results.  It does appear that oxidative stress has a major role in many clinical diseases.  We are not alone in this viewpoint.  There is a tremendous amount of human research data out there to support it.  In fact, an article was just released in May 2009 in the journal “Free Radical Biology & Medicine” by authors Ando and Fujita.  The article is titled “Metabolic Syndrome and Oxidative Stress” and details how oxidative stress is a key player in the development of insulin resistance in humans and how antioxidants seem to abolish or decrease the clinical disease.  Fascinating information.

Stay tuned for more….and thanks for viewing.

On a brighter note

Tags

, ,

As the title says, “on a brighter note”, we are seeing tremendous results with our Cur-OST product in horses afflicted with insulin resistance and laminitis or founder in laymen’s terms. Insulin resistance is a metabolic condition by which the cells in the body become somewhat non-responsive to insulin. Insulin is a hormone secreted by the pancreas and helps to drive sugar or glucose into the cells for energy production. In cases of insulin resistance, most horses are typically overweight due to excessive carbohydrates in their diets. The cells become resistant to the efforts of insulin and thus cellular function is impaired. Along with this, inflammation becomes a factor, secreting various inflammatory proteins and free radicals into the circulation. All of these factors come together and affect overall health. One of the biggest problems we see in horses, clinically, is laminitis or foundering. This is a very painful and debilitating condition of the feet. The condition can result in euthanasia due to excessive pain and quick progression of the condition. This is not unlike the condition that afflicted Barbaro and resulted in his untimely death. Our Cur-OST product is designed using “mother nature” to help reduce inflammatory protein production as well as “buffer” out free radicals. In most instances of insulin resistance in horses, we are forced to give pain medications as well as altering their diet. The process is rather slow and response rates can be variable. We have found that supplementation with our product brings about quick results in most of the patients, reducing pain and inflammation without the need for prescription medications in most cases. Rather fascinating stuff to say the least.